Cotrimoxazole (Sulfamethoxazole + Trimethoprim)
Co-trimoxazole is nothing more than the combination of sulfamethoxazole (a sulfonamide) and trimethoprim (another antibacterial) in a fixed ratio of 5: 1.
Most likely, this combination of active ingredients is better known under the trade name of Bactrim®.
Sulfamethoxazole - Chemical Structure
Trimethoprim - Chemical Structure
Unlike the single active ingredients that possess bacteriostatic activity (ie they are able to inhibit bacterial growth), their association allows to obtain a "bactericidal action (ie, when used together, they are able to kill bacterial cells). .
Co-trimoxazole is available in pharmaceutical formulations suitable for both oral and parenteral administration.