MICETAL ® - Flutrimazole

MICETAL ® is a drug based on Flutrimazole

THERAPEUTIC GROUP: Antifungals for topical use

Indications MICETAL ® - Flutrimazole

MICETAL ® is indicated in the treatment of dermatomycoses caused by fungi, yeasts and dermatophytes sensitive to Flutrimazole, in the treatment of cutaneous candidiasis, in the treatment of pityriasis versicolor and in the treatment of seborrheic dermatitis.

Mechanism of action MICETAL ® - Flutrimazole

MICETAL ®, a medicinal specialty based on Flutrimazole, is used in a dermatological clinic in the treatment of candidiasis and dermatomycoses caused by microorganisms sensitive to Flutrimazole.
Used topically, this active ingredient easily penetrates the membrane structures by inhibiting the enzyme Lanosterol 14alpha-demethylase and thus reducing the synthesis of ergosterol, an element responsible for the structural and functional properties of the plasma membrane.
The loss of these characteristics and the accumulation of catabolites with toxic potential seriously compromise the vital capacity of the cell, inducing its death and thus ensuring a prompt remission of symptoms.
The fungicidal, fungistatic and even bacteriostatic activity of MICETAL ® is also optimized by the excellent pharmacokinetic properties which considerably limit the systemic absorption of Flutrimazole, significantly reducing the risk of systemic and clinically noteworthy side effects.

Studies carried out and clinical efficacy

Mycoses. 2010 Nov; 53: 522-9. doi: 10.1111 / j.1439-0507.2009.01738.x.

Study to compare the efficacy and safety of fluconazole cream with flutrimazole cream in the treatment of superficial mycosis: a multicentre, randomized, double-blind, phase III trial.

Yim SM, Ko JH, Lee YW, Kim HW, Lee JY, Kim NI, Kye YC, Park KC, Choi JH, Lee KH, Kim MN, Kim KJ, Ro YS, Ahn KJ.

Clinical trial comparing the clinical efficacy of Flutrimazole to that of Fluconazole in the treatment of dermatomycosis, confirming the similar efficacy of the two active ingredients.

Rev Iberoam Micol. 1998 Mar; 15: 28-32.

[Review of the clinical efficacy of flutrimazole gel in the treatment of dandruff and / or seborrheic dermatitis.].

Noguera J, LerÃs E, Algueró M, Boncompte E, Izquierdo I; Grupo de trabajo flutrimazol gel.

Spanish study that demonstrates the good clinical efficacy of Flutrimazole, applied 3 times a week, in the treatment of seborrheic dermatitis, guaranteeing a good clinical result in the face of limited side effects.

Mycoses. 2003 Apr; 46 (3-4): 126-31.

Efficacy of flutrimazole 1% powder in the treatment of tinea pedis.

Pereda J, Noguera X, Boncompte E, Algueró M, Izquierdo I.

Study that demonstrates the efficacy of the application of 1% flutrimazole in powder form in the treatment of tinea pedis, showing a therapeutic efficacy similar to that observed for Bifonazole.

Method of use and dosage

1% cutaneous solution of Flutrimazole;
1% Flutrimazole cream for cutaneous use;
1% Flutrimazole gel for cutaneous use.
The choice of dosages, pharmaceutical format and duration of therapy is up to the dermatologist expert in the treatment of dermatomycosis, based on the clinical condition of the patient and the severity of the pathological picture.
Generally, the application of the appropriate amount of Flutrimazole directly on the skin region to be treated, once a day in the case of a cutaneous solution, 3 times a week in the case of using the gel, is sufficient to guarantee a remission of symptoms in a few weeks of treatment.

MICETAL ® warnings - Flutrimazole

The use of MICETAL ® must necessarily be preceded by an appropriate medical examination aimed at clarifying the infectious origin of the lesion and the consequent prescriptive appropriateness.
The patient on therapy with this medicine should avoid contact of the drug with eyes and mucous membranes, wash their hands thoroughly after applying the gel and follow all the appropriate medical indications to optimize the therapeutic efficacy of Flutrimazole, limiting its side effects.
Prolonged use of MICETAL ® could induce the onset of hypersensitivity reactions to the drug, requiring only rarely the suspension of the therapy in progress.


The use of MICETAL ® is generally contraindicated during pregnancy and in the subsequent breastfeeding phase.
Any use, justified only by real needs, should be carefully supervised by your gynecologist.


No drug interactions worthy of clinical note are currently known.

Contraindications MICETAL ® - Flutrimazole

The use of MICETAL ® is contraindicated in patients hypersensitive to the active substance or to one of its excipients.

Undesirable Effects - Side Effects

The application of MICETAL ® could determine the appearance of side effects, generally of a transitory nature and clinically not very relevant, such as burning, redness and erythema.
The side effects worthy of clinical note are much rarer.


MICETAL ® is a drug subject to mandatory medical prescription.

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