Mood tone: what it is and what it depends on

general; on the contrary, a state of bad mood corresponds to a condition of malaise that can affect various aspects of a person's life.

and very specific physiological processes. Going into more detail, the mood as well as the psyche in general are conditioned by the presence and activity of some neurotransmitters, such as dopamine, adrenaline and serotonin. These neurotransmitters known to be involved in mood regulation processes are produced starting from other molecules such as S-Adenosyl-Methionine, also known as SAMe or ademetionine.

SAMe has the ability to donate particular chemical groups known as "methyl groups" through a process called trans-methylation. This process is the basis of the synthesis and metabolism of various molecules essential for the life and functioning of the organism, among which we find, in fact, the neurotransmitters responsible for regulating the mood.

At the end of the trans-methylation process, S-Adenosyl-Methionine is transformed into homocysteine; the latter - with a process that requires the intervention of vitamin B12 and vitamin B9 (better known as folic acid) - is then converted back into SAMe and the cycle continues.

Any alteration in the chain of reactions that leads to the synthesis of mood-regulating neurotransmitters could therefore contribute to the appearance of mood alterations in a negative sense and lead to a series of consequences that can affect the overall well-being of the person.


In the most serious situations, when these negative mood swings persist for long periods of time, they can be linked or lead to real depressive phenomena.

, the tone of the mood can undergo considerable alterations, especially in a negative sense. Isolation - fundamental to try to contain the infections and the spread of the virus - and the fear of contagion, as well as the concern for the situation that has arisen to create in our country, in fact, can have repercussions on a psychological level.

Although the situation is constantly evolving, the restrictions and limitations - although necessary for the protection of everyone's health - do not always allow us to carry out normal daily activities; to all this are added the concerns for one's work, as well as for the health emergency itself, for one's own health and for that of loved ones, the impossibility of carrying out physical activity as one used to do and following a "nutrition that is not always healthy and balanced (thus not guaranteeing the supply of all the nutrients needed by our body). What has been said so far represents only some of the most common factors that can contribute to lowering the mood and increasing stress in a context of health emergency such as the current one.

It is important to underline that such sensations and lowering of mood are more than understandable and that in this difficult situation it is important to adopt an attitude that is as positive as possible.

and regular physical activity, even if done at home. With the correct diet, in fact, we guarantee our body the right amount of all the nutrients necessary for its proper functioning; while physical activity, as we know, plays a very important role in maintaining a good mood balance.

Even the attitude of accepting what disturbs us and that triggers the lowering of the mood represents one of the fundamental steps to overcome the most difficult moments, as well as sharing one's emotions with loved ones in order to get out of isolation. that the same low mood is able to induce.

If the adoption of positive and proactive behaviors and attitudes does not help to resolve the situation, it is advisable to contact your doctor who will be able to indicate which remedies or treatments may be most useful to your client to restore his mood as soon as possible.

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